We haven't been able to get this option to work properly on Quest. The app will just show a black screen (presumably waiting for a debugger) but even after attaching the debugger through Visual Studio, it doesn't continue the app process. So it just hangs. Confirmed on both IL2CPP and Mono backends.
For most systems this option causes a popup on the Android device that must be accepted. I would assume this pop up isn't showing properly and causes Unity to get in a weird state.