I have to play seated, so I've been trying them all that way. The most frustrating part is not being able to turn around. Need to find a solution to that. VR Sports was painful. I have fractures in my spine/back, which is why I can't stand for more than a couple of minutes. Sports was cool, but really hurt. Won't be playing that again, but definitely playable seated for most people.
Another problem is that sometimes objects you're supposed to grab are below your legs. For example, with The Unspoken, I had a hard time grabbing charms because I would have to put my hand through my legs to get to them. It expects you to be standing. It would be better if they put them a little further in front of you.
Drawing my weapon in Dead and Buried was a bit annoying too for similar reasons. I tried a single multiplayer match and lost hard.
Still, they're all mostly playable.