I don't have the problem but I guess you may have some reaction to the foam padding. Maybe an alternative face pad might solve the problem. I can recommend the medical grade silicon covers from VRCover. https://vrcover.com/item/oculus-quest-2-silicone-cover/
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Are you using the default strap? Even if you don't have an allergy, the Quest can still put a lot of pressure on your cheeks.
Some peoples' skin reacts strongly to pressure.
The Elite Headstrap helps a lot, and the Deluxe Audio Strap takes almost all the pressure off your cheeks.
The silicon covers are also nice. I can't stand getting my headset back with someone else's sweat on it. You can just wipe the silicon clean and it's hypoallergenic. So, I can second that.