Most games (if not all) on the Store (and on Steam) will have a comfort rating on the game page...some games that involve locomotion that I have seen will have options for movement type but I guess it just depends on the game...as far as I am aware (but dont quote me on this) there isn't a universal comfort option.
When Einstein was asked how it felt to be the smartest man on Earth, he replied, “I wouldn’t know. Ask Nikola Tesla”.